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The Chemistry of Snake Venom

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  • Uploaded 11 months ago in the category Education

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    We know poisonous snakes are dangerous, but what exactly makes venom so powerful? Evolutionary biology tells us why venom is useful for snakes, but chemistry tells us how venom works.

    This week, Reactions sheds some light on the proteins in venom, as well as its potential medical uses

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    Music:
    Robert Daglio – Mr.

    Fantastic
    Sam Leopard – Back for More

    Writer & Producer:
    Kirk Zamieroski

    Executive Producer:
    Adam Dylewski

    Scientific consultants:
    Kenneth Winkel, Ph.D.
    Darcy Gentleman, Ph.D.
    Sophia Cai

    SOURCES:
    Snake Venom Basics - http://www.chm.bris.ac.uk/webprojects2003/stoneley/two.htm

    Snake Venom Basics 2 - http://www.toxinology.com/fusebox.cfm?staticaction=snakes/ns-snvenom.htm

    Cytotoxins - http://www.omicsonline.org/open-access/metalloproteinases-mechanisms-of-action-and-pharmacological-relevance-2161-0495.1000-181.pdf

    Striking Beauties: Venomous Snakes - https://web.archive.org/web/20060523055642/

    General Neurotoxins - http://www.chemistryexplained.com/Ne-Nu/Neurotoxins.html

    Evolutions Most Effective Killer: Snake Venom - http://www.popsci.com/scitech/article/2008-03/evolution’s-most-effective-killer-snake-venom

    Venom and alzheimer’s - http://www.med.monash.edu.au/news/2016/snake-venom-alzheimers-disease.html

    Blood clotting hydrogels - http://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.5b00356
    Annual snakebites - http://www.cdc.gov/niosh/topics/snakes/

    Prothrombin activation - http://www.ncbi.nlm.nih.gov/pubmed/3531198

    Fibrin & clotting - http://atvb.ahajournals.org/content/31/12/e88.full

    On thrombin and fibrin - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408736/

    Microclots - https://books.google.co.jp/books?id=FBclBQAAQBAJ&pg=PA116&lpg=PA116&dq=venom+microclots+thombrin&source=bl&ots=_Pf4W7ImrS&sig=sBn0Cgwlzo7zKuVHbd1HrjdMcTQ&hl=en&sa=X&ved=0ahUKEwiR6qrK7_vLAhWJFJQKHev5BAAQ6AEIKDAC#v=onepage&q=venom microclots thombrin&f=fals

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